Therapy protocols – Past, present and future

Georgiana-Eliza Murgu⁽¹⁾, Elena Rezuș^(2,3,*)

1)“Saint Parascheva” Clinical Hospital of Infectious Diseases Hospital, Iași, Romania
2)“Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania
3)Rheumatology I Clinic, Clinical Hospital of Rehabilitation, Iași, Romania

Since autoimmune rheumatic diseases comprise a large variety of diseases, with different types of manifestations, there is a real need for a well defined treatment strategy. This comprises, among others, the window of therapeutic opportunity concept and the treat-to-target strategy. Once these elements are in place, there is another need for conceiving therapeutic protocols, usually on a national level, that combine the medical information contained in specific guidelines as well as the economic constraints of each health system. This paper aims at reviewing these key concepts and the some of the national therapeutic protocols concerning the most common autoimmune rheumatic diseases.

Keywords: autoimmune rheumatic diseases, treat-to-target, biologic DMARD, targeted sintetic DMARD

Corresponding author(s): Elena Rezus, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, Romania, e-mail: elena_rezus@yahoo.com